A Modified Bacillus Calmette-Guérin (BCG) Vaccine with Reduced Activity of Antioxidants and Glutamine Synthetase Exhibits Enha

Trehalose Mycolates Calmette-Guérin Is Due Principally to Bacillus Mycobacterium bovis of In Vivo Activity of Released Cell Wall Lipids

Reducing the Activity and Secretion of Microbial Antioxidants Enhances the Immunogenicity of BCG

BACKGROUND In early clinical studies, the live tuberculosis vaccine Mycobacterium bovis BCG exhibited 80% protective efficacy against pulmonary tuberculosis (TB). Although BCG still exhibits reliable protection against TB meningitis and miliary TB in early childhood it has become less reliable in protecting against pulmonary TB. During decades of in vitro cultivation BCG not only lost some gene...

Reactive arthritis following Bacillus Calmette-Guérin immunotherapy

2014 Bacillus Calmette-Guérin (BCG) is a vaccine derived from attenuated strains of Mycobacterium bovis. Mycobacterium bovis BCG-based therapy is considered an effective alternative for bladder carcinoma in situ when exclusive transurethral resection is inadequate. Among the complications associated with therapy, there are few reports in the literature on reactive arthritis. We report the case ...

Infection Promotes Virus Clearance and Protects from by Recombinant Bacillus Calmette-Guérin Syncytial Virus-Specific Th1 Cells Induced Efficient Lung Recruitment of Respiratory

Bacillus Calmette-Guérin Mycobacterium bovis Vaccine Efficacy of Glycolipids Enhances Immunogenicity and Incorporation of NKT Cell-Activating